Search for and download brochures, application notes, presentations and posters.
Read our Blog!
Search here for recent application notes from Anatune and our partners.
We organise our own events and attend many others.

We love to talk with our customers face-to-face so, if you are attending an event, let us know and we can arrange to meet.
Lunch & Learn seminars are provided free by Anatune and consist of one-hour sessions, conducted by experienced analytical chemists, covering topics that are relevant to the work you do.
Download copies of recent presentations given by the Anatune team.
Here you can download copies of recent posters presented by the Anatune team and our partners.
Who we are, what we do and what we believe is important.
We recognise that data quality, analytical flexibility and effective support should be our primary concern and Anatune is dedicated to delivering these benefits to analysts in the UK and Ireland.
Our first priority is to maintain a great team spirit and we only employ people with great attitudes.

We believe in continual learning and personal development. We train our staff well.

Find out more about them here.
Our role is to bring the World's best analytical technologies to laboratories in the UK and Ireland.

We do this in partnership with some great companies.
We do our best work and achieve the very best outcomes when collaborating with our customers.
We have built strong, long-term relationships with customers resulting in repeat business and an unbeatable reputation for reliability and trust.

Here's what they say about us...
While it’s certainly not our primary motivation, peer recognition is important to us. See our latest and greatest achievements here.

Automatic Liner Exchange (ALEX) to Deal with Dirty Matrices Using the GC/Q-TOF

Application Note

The use of non-selective extraction protocols, such as QuEChERS (Quick Easy Cheap Effective Rugged and Safe) can result in dirty sample extracts, which can mean deterioration of chromatographic performance and the need to replace inlet liners frequently. The use of the GERSTEL Automated Liner EXchange (ALEX) was demonstrated for the analysis of Pesticides in Coriander extracts. This matrix was chosen as representative of a ‘dirty’ plant matrix containing a number of non-volatile components. The liner was changed every 5 injections and linearity and precision experiments were performed. No chromatographic deterioration was observed and RSDs of <10% were achieved (without IS) for a sample spiked at 50 ng/L. This work was performed on the Agilent GC/Q-TOF and also demonstrated the increased selectivity (and hence sensitivity) achievable using accurate mass for target compounds – due to the ability to extract a more selective mass range and thus reduce noise from any remaining matrix interferences.  The use of ALEX also reduces the need for instrument maintenance, thus reducing down time and increasing sample throughput.

Application Note Downloads

Automatic Liner Exchange (ALEX) to Deal with Dirty Matrices Using the GC/Q-TOF


Leave a Reply

Your email address will not be published. Required fields are marked *

Time limit is exhausted. Please reload CAPTCHA.